Toxicological data analysis to support grouping of pesticide active substances for cumulative risk assessment of effects on liver, on the nervous system and on reproduction and development

Gerrit Wolterink; Petra van Kesteren; Karin Mahieu; Bianca van de Ven; Bernadette Ossendorp; Laura Ruggeri; Luca Tosti; Francesca Metruccio; Christian Schlitt; Angelo Moretto; Nathalie Printemps; Marie‐Estelle Gouze; Sandrine Charles; Karine Angeli; Antony Fastier; Thierry Mercier

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Toxicological data analysis to support grouping of pesticide active substances for cumulative risk assessment of effects on liver, on the nervous system and on reproduction and development

机译：毒理学数据分析，以支持将农药活性物质分组，以累积风险评估对肝脏，神经系统以及生殖和发育的影响

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Toxicological data analysis to support grouping of pesticide active substances for cumulative risk assessment of effects on liver, on the nervous system and on reproduction and development.

机译：毒理学数据分析可支持对农药活性物质进行分组，以便对肝脏，神经系统以及生殖和发育的影响进行累积风险评估。

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《EFSA supporting publications》 |2013年第1期|共88页
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Gerrit Wolterink; Petra van Kesteren; Karin Mahieu; Bianca van de Ven; Bernadette Ossendorp; Laura Ruggeri; Luca Tosti; Francesca Metruccio; Christian Schlitt; Angelo Moretto; Nathalie Printemps; Marie‐Estelle Gouze; Sandrine Charles; Karine Angeli; Antony Fastier; Thierry Mercier;
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中图分类食品安全与卫生;
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1. Applicability of QSAR analysis in the evaluation of developmental and neurotoxicity effects for the assessment of the toxicological relevance of metabolites and degradates of pesticide active substances for dietary risk assessment [J] . Andrew Worth, Mojca Fuart‐Gatnik, Silvia Lapenna, EFSA supporting publications . 2011,第6期

机译：QSAR分析在评估发育和神经毒性作用以评估代谢物和农药活性物质降解物在饮食风险中的毒性相关性中的适用性
2. Applicability of QSAR analysis to the evaluation of the toxicological relevance of metabolites and degradates of pesticide active substances for dietary risk assessment [J] . EFSA supporting publications . 2010,第5期

机译：QSAR分析在评估膳食风险评估中农药活性物质代谢物和降解物的毒理学意义上的适用性
3. Critical evaluation of observed adverse effects of endocrine active substances on reproduction and development, the immune system, and the nervous system [J] . OConnor JC., Chapin RE. Pure and Applied Chemistry . 2003,第11a12期

机译：严格评估观察到的内分泌活性物质对生殖和发育，免疫系统和神经系统的不良影响
4. Application of the Maximum Cumulative Ratio (MCR) Approach Using Residue Data from Pesticide Data Program and the Cumulative and Aggregate Risk Evaluation System (CARES) Model [C] . B. M. Young, P. Price Annual conference of the International Society of Exposure Science . 2014

机译：利用农药数据程序中的残留数据以及累积和总体风险评估系统（CARES）模型应用最大累积比率（MCR）方法
5. Toxicological evaluation of urban-related contaminants in estuarine ecosystems: 1. Effects of contaminants on the development and reproduction of the estuarine copepod Amphiascus tenuiremis; and 2. the role of sediment constituents on pesticide bioavailability to the estuarine bivalve Mercenaria mercenaria. [D] . Bejarano, Adriana C. 2004

机译：河口生态系统中与城市有关的污染物的毒理学评估：1.污染物对河口co足类两栖类双歧杆菌的发育和繁殖的影响； 2.沉积物成分对河口双壳类Mercenaria mercenaria农药生物利用度的作用。
6. Cumulative dietary exposure assessment of pesticides that have acute effects on the nervous system using SAS® software [O] . European Food Safety Authority (EFSA), Bruno Dujardin, Valentina Bocca 2019

机译：使用SAS的累积膳食暴露评估对神经系统有急性影响的农药®软件
7. Toxicological data analysis to support grouping of pesticide active substances for cumulative risk assessment of effects on liver, on the nervous system and on reproduction and development [O] . Gerrit Wolterink, Petra van Kesteren, Karin Mahieu, 2013

机译：毒理学数据分析，支持对肝脏作用累积风险评估的农药活性物质的分组，在神经系统和繁殖与发展中
8. Assessment of Risks to Human Reproduction and to Development of the Human Conceptus from Exposure to Environmental Substances [R] . Galbraith, W. M., Voytek, P., Ryon, M. G. 1982

机译：评估人类生殖风险和暴露于环境物质的人类概念的发展

Toxicological data analysis to support grouping of pesticide active substances for cumulative risk assessment of effects on liver, on the nervous system and on reproduction and development

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