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Bilateral Subtrochanteric Pseudofractures of the Femur Secondary to Osteomalacia: a case report

机译:继发骨质疏松的股骨双侧转子下假性骨折:一例报告

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Introduction: Nutritional osteomalacia is a metabolic bone disorder common among the Asian female immigrant population in the United Kingdom. It is often under diagnosed in the United Kingdom, although it has been highlighted in the literature since the 1960s.1 Patient may be asymptomatic in the early stages although signs of osteomalacia may be apparent on X-ray pictures or other diagnostic tests. As osteomalacia worsens, symptoms may include bone pain, decreased muscle tone and muscle weakness. Pathological fractures such as bilateral subtrochanteric pseudofractures of the femur are an uncommon complication of osteomalacia. This has been rarely reported. Case presentation: This case presents an interesting and unusual case of a 38-year-old female of Asian origin with bilateral subtrochanteric pseudofractures of the femur secondary to osteomalacia. The patient was treated successfully with calcium and vitamin D supplement therapy without surgical intervention. The bone pain subsided and she was able to bear full weight within 2 weeks of treatment. Conclusion: There should be a high index of suspicion of this disease, particularly among Asian female immigrant population presenting with persistent and non-specific musculoskeletal pain and on strict vegetarian diet. This case reiterates the importance of considering insufficiency or stress fractures in this group of patient. Management of the underlying cause, osteomalacia proves vital to prevent further complications. Morbidity related to delayed treatment has been well documented, so a high level of clinical suspicion is imperative. Introduction Nutritional osteomalacia is a metabolic bone disorder common among the Asian female immigrant population in the United Kingdom. It is often under diagnosed in the United Kingdom, although it has been highlighted in the literature since the 1960s.1 Patient may be asymptomatic in the early stages although signs of osteomalacia may be apparent on X-ray pictures or other diagnostic tests. As osteomalacia worsens, symptoms may include bone pain, decreased muscle tone and muscle weakness. Pathological fractures such as bilateral subtrochanteric pseudofractures of the femur are an uncommon complication of osteomalacia. Early recognition of this type of pathological fractures leads to the appropriate treatment, including medical and surgical treatment to avoid serious complications. Case presentation A 38-year-old female of Asian origin who was a vegetarian presented with a six-month history of intermittent bilateral hip pain. She had experienced generalised malaise, some discomfort in the groin for the past few months on walking and recalled losing her balance. There was no history of direct trauma. Her past medical history included hypothyroidism and she was on 125 mcg levothyroxine daily. She did not drink alcohol or smoke. Since moving to the United Kingdom from India two years earlier, she had stayed indoors most of the time and had very little exposure to the sun. On examination, she was slim and walked with a waddling gait. Movements of both hips were mildly painful on abduction and internal rotation. No other obvious abnormality was found. The kidney, liver, bone profile and thyroid function tests were all normal. The anteroposterior radiograph of the pelvis showed bilateral undisplaced subtrochanteric pseudofractures of the femur. The radiograph changes were suggestive of pseudofracture secondary to osteomalacia. She was treated with therapeutic doses of calcium and vitamin D supplements but had no surgical intervention. She was advised to increase her calcium intake by consuming dairy and poultry products, especially eggs and milk. She was discharged 2 weeks later when the bone pain subsided and able to bear full weight.
机译:简介:营养性骨软化症是一种代谢性骨疾病,在英国的亚洲女性移民人群中很常见。尽管自1960年代以来在文献中对此进行了强调,但通常在英国对其进行诊断。1尽管在X射线照片或其他诊断检查中可能出现骨软化​​的迹象,但患者在早期可能没有症状。随着骨软化症的恶化,症状可能包括骨痛,肌肉张力降低和肌肉无力。诸如股骨双侧转子下假性骨折等病理性骨折是骨软化症的罕见并发症。鲜有报道。病例介绍:本病例为一名有趣的,不寻常的病例,该病例为一名来自亚洲的38岁女性,继发于骨软化症,其股骨转子下假性双侧骨折。无需手术干预即可成功使用钙和维生素D补充疗法治疗该患者。骨痛消退,她能够在治疗的2周内承受全部重量。结论:应该高度怀疑这种疾病,尤其是在亚洲女性移民人群中,他们表现出持续的和非特异性的肌肉骨骼疼痛以及严格的素食饮食。该案例重申了在这一组患者中考虑供血不足或应力性骨折的重要性。处理潜在的病因,骨软化症对预防进一步的并发症至关重要。与延迟治疗相关的发病率已被充分证明,因此必须进行高度的临床怀疑。简介营养性骨软化症是一种代谢性骨疾病,在英国的亚洲女性移民人群中很常见。尽管自1960年代以来在文献中对此进行了强调,但通常在英国对其进行诊断。1尽管在X射线照片或其他诊断检查中可能出现明显的骨软化迹象,但患者在早期可能没有症状。随着骨软化症的恶化,症状可能包括骨痛,肌肉张力降低和肌肉无力。诸如股骨双侧转子下假性骨折等病理性骨折是骨软化症的罕见并发症。对这种类型的病理性骨折的早期认识导致了适当的治疗,包括避免严重并发症的医学和外科治疗。病例介绍一名来自亚洲的38岁女性,是一名素食主义者,有六个月的双侧间歇性髋部疼痛病史。她经历了全身不适,在过去的几个月中,在步行时腹股沟有些不适,并回忆起失去了平衡。没有直接创伤史。她过去的病史包括甲状腺功能减退症,每天服用125 mcg左甲状腺素。她不喝酒也不抽烟。自两年前从印度移居英国以来,她大部分时间都呆在室内,几乎没有阳光。经检查,她苗条,步态蹒跚。在外展和内旋时,双髋的动作均轻度疼痛。未发现其他明显异常。肾脏,肝脏,骨骼和甲状腺功能检查均正常。骨盆的前后X线片显示双侧股骨转子下假性假性骨折。 X射线照片的改变提示继发于骨软化症的假性骨折。她接受了治疗剂量的钙和维生素D补充剂的治疗,但没有进行手术干预。建议她通过食用乳制品和家禽产品(尤其是鸡蛋和牛奶)来增加钙的摄入量。 2周后,当骨痛消退并能够承受全部重量时,她出院了。

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