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Chronic Exposure to Extremely Low Frequency Electromagnetic Field Induces Mild Renal Damages in Rats

机译:慢性暴露于极低频电磁场可引起大鼠轻度肾脏损伤

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The kidney is a major potential route for the absorption of hazardous materials encountered in the environment. The aim of this study was to evaluate the influence of ELFEMF on function and structure of kidney in rats. Experimental adult male Wistar rats were exposed to a 50 Hz ELFEMF, 1 mT (emitted from solenoid) for 24 h daily during 135 days. The sham rats were subjected to sham exposure and the control rats were kept in animal room. In final, blood samples collected for the determination of the creatinine, urea nitrogen, albumin, globulin and total protein concentration in the plasma. The kidney was examined using light microscopy. Results showed that in EMF exposed group plasma concentration of creatinine and urea nitrogen was increased (0.001) which was accompanied by marked vascular congestion in the renal cortex and reduction in red blood cell count in glomerular capillaries but there were no changes in total protein, albumin and globulin levels. In conclusion, long term exposure to ELFEMF impacts renal function by influencing the perfusion of kidney.
机译:肾脏是吸收环境中遇到的有害物质的主要潜在途径。这项研究的目的是评估ELFEMF对大鼠肾脏功能和结构的影响。实验成年雄性Wistar大鼠在135天内每天暴露于50 Hz ELFEMF,1 mT(由电磁线圈发射),持续24 h。对假大鼠进行假暴露,将对照组大鼠放在动物室内。最后,采集血样以确定血浆中的肌酐,尿素氮,白蛋白,球蛋白和总蛋白浓度。使用光学显微镜检查肾脏。结果显示,在EMF暴露组中,肌酐和尿素氮的血浆浓度增加(0.001),伴随着肾皮质的明显血管充血和肾小球毛细血管的红细胞计数减少,但总蛋白,白蛋白没有变化和球蛋白水平。总之,长期接触ELFEMF会影响肾脏的灌注,从而影响肾脏功能。

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