IN VITRO EVALUATION OF ANTIMICROBIAL ACTIVITIES OF CRUDE EXTRACTS FROM MURRAYA KOENIGII AGAINST PATHOGENIC BACTERIA

摘要

Murraya koenigii, curry leaf is found almost throughout India up to an altitude of 1500 m. It is much cultivated for its aromaticity and is used in South India as a natural flavouring agent in various curries. The present study deals with the antimicrobial activities which confirmed that the methanol extracts of leaves are active against K. pneumoniae and S. typhi with maximum inhibition and moderate effect against other four bacteria. Which was then followed by Aqueous, chloroform and petroleum ether extracts showed better activity against P. aeuriginosa, E. coli and S. typhi. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of the water, ethanol, chloroform and pet ether extracts were in the range of 12.5 to 100.0 mg/ml and 50.0 to 100.0 mg/ml, respectively. Amongst the evaluated extracts, the ethanolic extract showed the strongest antibacterial effect. Hence, present study is useful towards authenticating the taken specimen to be a potent antimicrobial