Antimicrobial activity of bioactive molecules isolated from filamentous fungi

摘要

Various microorganisms display antagonism as a principle phenomenon for the production of secondary metabolites. The present study aims at employing this antagonistic property of fungi for the production of some useful bioactive secondary metabolites. 53 isolates were screened for the production of antimicrobials after the incorporation of lactose which triggered the production of secondary metabolites, out of which only 3 showed positive results against the test pathogens. These were identified as Aspergillus flavus var flavus, Acremonium cellulolyticus and Aspergillus chevialeri. The FTIR spectrum revealed the presence of various functional groups such as amines, amides, carboxylates, alcohols, alkanes, alkynes, nitro groups, etc. The knowledge of these components can be further employed for the production of pharmaceutically important products in due course of time.