SOLUBILITY AND DISSOLUTION RATE ENHANCEMENT OF OLMESARTANMEDOXOMIL BY CHITOSAN BASE CO-CRYSTAL APPROACH

摘要

Co-crystal of Olmesartan Medoxomil were prepared by solvent change technique. chitosan solution was prepared by soaking chitosan and chitosan chlorhydrate in glacial acetic acid. A weighed amount of drug was dispersed in chitosan solution by stirring. The