DETERMINATION OF CHEMICAL COMPOSITION OF ESSENTIAL OIL PORTION OF REPUTED MARKETED UNANI FORMULATION ZINDA TILISMATH

摘要

Zinda. Tilismath. is.an. ancient. unani.formula. prepared. from.selected. herbs. extremely. effective. in.treating. several. common. ailments. like.cough,.blocked. nose,. Indigestion,. Stomach. disorder,. etc.. claimed. by. the. manufacturer.. Nowadays,. it. has. become. a. necessity. that. for. wider.promotion,.exceptancy,.sales.and.export.of.the.medicinal.product.scientifically.proved.data.helps.in.larger.voluminous.sales..Hence.in.the.present.preliminary.phytochemical. investigations. an. attempt. has. been. to. check. the. chemical. composition. of. the. essential. oil. portion. of. Zinda.Tilismath.3. μl. of. the.sample.solution.was.directly.injected.into.the.Shimadzu.GC‐MS‐QP2010. Plus. apparatus. equipped. with. quadrapole. detector. and. spli t. injection.system..MS. spectra.of.separated.compounds. were. compared. with.one. from. Wiley.7. Nist.05. mass. spectral.database.. The. identity. of. the.spectra.above.95%.was.needed.for.the.identification.of.compounds..The.chemical.composition.of.essential.oil.portion.of.the.formulation .was.determined.by.GC‐MS. analysis.. . Eight. compounds. constituting. about. 90.58%. of. the. essential. oil. were. identified.. The. main. components. were. L‐limonene,.Tetradecane,.Decane,.Isoborneal,.Camphor,.Terpane,.Cymol.&.Alpha‐Pinene..The.outcome.of.this.study.is..essential.oil.portion.of.the.Zinda.Tilismath.contain.terpenes.and.their.oxygenated.derivatives,.which.are. believed.to.be.highly.effective.antibacterial,.antifungal,.analgesic,.anti‐inflammatory,.antioxidant.&.spasmolyticis..The.above.eight.major.compounds.of.the.formulation.can.be.regularly.be.checked.for.their.detection.&.quantification.in.routine.quality.control.of.these.herbal.formulation