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首页> 外文期刊>International Journal of Pharmacy and Pharmaceutical Sciences >CHROMATOGRAPHIC FINGERPRINT ANALYSIS OF DITERPENOIDS AND SESQUITERPENOIDS IN N-HEXANE EXTRACT OF EMILIA SONCHIFOLIA (L.) DC BY HPTLC TECHNIQUE
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CHROMATOGRAPHIC FINGERPRINT ANALYSIS OF DITERPENOIDS AND SESQUITERPENOIDS IN N-HEXANE EXTRACT OF EMILIA SONCHIFOLIA (L.) DC BY HPTLC TECHNIQUE

机译:高效液相色谱法(HPLC)分离苦中正己烷提取物中双萜和半萜类化合物的色谱指纹图谱。

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摘要

Objective: The main objective of the study is to investigate the chemical fingerprint profile of diterpenoid and sesquiterpenoids of E. sonchifolia (L.) DC. using High Performance Thin Layer Chromatography (HPTLC) technique. Methods: HPTLC profile of diterpenoid and sesquiterpenoids were done and profiles were developed for authentication. Results: The n-hexane extract of E. sonchifolia showed the presence of diterpenoids in the standard but absent in the sample with different Rfvalues in the range of 0.01 to 0.61 but the sesquiterpenoids is present in both the standard as well as the sample with different Rfvalues in the range of 0.01 to 0.93. Conclusion: Based on the results it can be concluded that the n-hexane extract of E. sonchifolia is the potential natural resources for pharmacology and functional foods. The development of such fingerprinting from the aerial parts of E. sonchifolia is useful in differentiating the species from the adulterant and act as biochemical markers in the pharmaceutical industry and plant systematic studies. In future, the bioactive compounds will be isolated from this plant which may lead to the formation of new drugs against various diseases
机译:目的:本研究的主要目的是调查索氏大肠杆菌(E. sonchifolia(L.)DC)的二萜和倍半萜的化学指纹图谱。使用高性能薄层色谱(HPTLC)技术。方法:完成了二萜和倍半萜的HPTLC分析,并开发了用于鉴定的分析。结果:大肠杆菌的正己烷提取物在标准物中存在二萜类化合物,但在Rf值介于0.01至0.61范围内的样品中不存在二萜类化合物,但在标准品和不同样品中均存在倍半萜类化合物Rf值在0.01到0.93之间。结论:根据结果,可以得出结论,厚皮大肠杆菌的正己烷提取物是药理学和功能性食品的潜在自然资源。从海泡参的气生部分发展出这种指纹图谱有助于区分物种和掺假物,并在制药工业和植物系统研究中充当生化标记。将来,将从该植物中分离出生物活性化合物,这可能导致形成抗多种疾病的新药

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