Chronic histiocytic intervillositis- a rare placental cause of poor obstetric outcome: a clinicopathological study and literature review

摘要

Chronic histiocytic intervillositis (CHIV) of the placenta is a rare and poorly understood entity which may occur in all trimesters of pregnancy. Till date about 60 cases of CHIV has been reported, with high rate of recurrences in subsequent pregnancies. There is increased risk of perinatal mortality and fetal growth restriction in this group, hence diagnosing CHIV becomes important to predict the outcome of subsequent pregnancies and also to understand the pathogenesis, thus treatment choices. Here in, we present a case of CHIV in a primigravida with second trimester pregnancy loss.