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Use of a local anesthetic and opioid combination in spinal anesthesia in short urologic surgeries

机译:局部麻醉和阿片类药物联合在短期泌尿外科手术中在脊髓麻醉中的应用

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Background: To investigate how low-dose levobupivacaine affects both surgical comfort and hemodynamics in patients undergoing short urologic procedures using spinal anesthesia. Methods: Our study was conducted prospectively and double-blind. The study group comprised 40 patients aged 18-65 years from the ASA I-III risk group who had undergone short urological interventions, randomly split into two groups. Informed consent and ethics committee approval were received. Using a media approach and placed in the lateral decubitus position, the patients were given spinal anesthesia using 22 G catheter. Group L was given 1.5ml of levobupivacaine (7.5mg) at 0.5% concentration +0.5ml of saline. Group LF was given 1.2ml levobupivacaine (6mg) at 0.5% concentration +25μg fentanyl (0.5ml) +0.3ml saline. Patient data including peripheral oxygen saturation; systolic, diastolic, mean arterial pressure; time to first postoperative need for analgesics, and spinal block characteristics were recorded at 3, 5, 10, 15, 30, 60, 120 and 360minutes after spinal anesthesia. Results: No significant differences were observed in the demographic and hemodynamic data between groups. Motor blocks were seen to wear off more in Group LF than in Group L at 120minutes. Group LF required first postoperative analgesics later than Group L; this difference was not significant. Conclusions: Sufficient anesthesia was achieved in both groups via spinal block using local anesthetic or local anesthetic plus opioid for relatively short urological procedures. The latter group recovered faster.
机译:背景:研究低剂量左旋布比卡因对使用脊髓麻醉进行短期泌尿外科手术的患者的手术舒适性和血液动力学的影响。方法:我们的研究是前瞻性和双盲的。该研究组包括来自ASA I-III风险组的40位年龄在18-65岁的患者,他们接受了短暂的泌尿外科干预,随机分为两组。已获得知情同意和道德委员会批准。使用媒体方法并放置在外侧卧位,使用22 G导管对患者进行脊柱麻醉。 L组给予0.5ml浓度的0.5ml左旋布比卡因(7.5mg)+ 0.5ml盐水。 LF组给予0.5%浓度的1.2ml左旋布比卡因(6mg)+25μg芬太尼(0.5ml)+ 0.3ml盐水。患者数据包括外周血氧饱和度;收缩压,舒张压,平均动脉压;首次术后需要镇痛药的时间,并且在麻醉后3、5、10、15、30、60、120和360分钟记录了脊柱阻滞特征。结果:两组之间在人口统计学和血液动力学数据上均未观察到显着差异。在120分钟时,LF组中的马达块比L组中的磨损更多。 LF组在L组之后需要首先进行术后镇痛。这种差异并不明显。结论:两组均通过局部麻醉或局部麻醉加阿片类药物经较短时间的泌尿外科手术通过脊髓阻滞实现了充分麻醉。后一组恢复得更快。

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