Radical Scavenging Activity and Phenolic Contents of Brown Seaweeds Harvested from the Coast of Sidi Bouzid (El Jadida, Morocco)by Nazha Samri, Laila Hsaine, Soukaina El Kafhi, Samira Khlifi, Samira Etahiri, Morocco

摘要

Antimicrobial agents are some of the most widely, and often injudiciously, used therapeutic drugs worldwide. Important considerations when prescribing antimicrobial therapy include obtaining an accurate diagnosis of infection; understanding the difference between empiric and definitive therapy; identifying opportunities to switch to narrow-spectrum, cost-effective oral agents for the shortest duration necessary. The objective of the study is to evaluate the overall usage and outcome of meropenem in hospital in order to promote the rational prescribing, dispensing, and administration. The prospective observational study of meropenem usage was conducted in different Intensive Care Units and Wards of a 220 bedded tertiary care teaching hospital to assess rational use of meropenem. The study was conducted by reviewing file of 173 admitted patients who received meropenem during march 2018 to June 2018. In this study it was found that most of the patients were administered correct doses. Though over dosing and under dosing were observed in few cases and dosing modifications were required for some cases. During this study fosfomycin used frequently along with meropenem therapy. It was also found that meropenem used empirically in maximum cases. According to this study it was found that meropenem was safe for elderly patients as the number of ADR was negligible. The study showed that dosing accuracy of meropenem as per standard dosing guideline was used in most patients. However frequent inappropriate use (As per sensitivity results) of meropenem was also noted in the study which could lead to increase of antibiotic resistance in the health-care system.