A Review on Hepatoprotective Medicinal Plants

摘要

The Liver is a vital organ involved in the maintenance of metabolic functions and detoxification of the exogenous and endogenouschallenges like xenobiotic drugs, viral infections and chronic alcoholism. Liver diseases are a major worldwide health problem, withhighly causing disorder in developing countries. They are mainly caused by chemicals and some drugs when taken in very high doses.Despite advances in modern medicine, there is no effective drug available that stimulates liver function, offer protection to the liverfrom damage or help to regenerate hepatic cells. There is urgent need, therefore, for effective drugs to replace supplement those incurrent use. Herbal remedies are focused in the pharmaceutical industry to evolve a safe route for liver disorders. Medicinal plantshave been considered as important therapeutic aid for alleviating ailment of humankind. Herbal medicines have been used in thetreatment of liver diseases for a long time. The present review is aimed at compiling data based on reported works on promisingmedicinal plants that have been tested for their hepatoprotective activity in different hepatotoxicity induced models. Thebiochemical and pathological mechanism of hepatotoxicity has been also discussed in present review.