Magnetic Nanoparticles: Magnetic Nano-Technology Using Biomedical Applications and Future Prospects”

摘要

The present study was designed to study the impact of Piper betel leaf stalk extract on sperm count, pH, motility, and mortality on semen of Swiss albino male mice. The betel leaf stalk aqueous extracts was administered orally at the dosage of 0.15ml (50mg/kg/body weight) for 10, 20, 30, 40, and 50 days. The investigation was carried out on seminal parameters analysis. Treatment of aqueous extract of Piper Betel Leaf Stalk caused significant decrease in sperm count during 20 (P<0.01), 30 (P<0.01), 40 (P<0.001) and 50 (P<0.001) days treatment than the control. Motility of spermatozoa also decrease in treated mice significantly after 20 (P<0.01), 30 (P<0.001), 40 (P<0.001) and 50 (P<0.001) days treatment than the control. The pH of seminal plasma also decline significantly in treated male mice after exposure during 30 (P<0.01), 40 (P<0.001)and 50 days (P<0.001) than the control. However mortality of the spermatozoa increases significantly and rapidly in treated mice during 20 (P<0.01), 30 (P<0.001), 40 (P<0.001) and 50(P<0.001) days than the control. Such significant alteration suggest that aqueous extract of Piper betel leaf stalk produced adverse effects in seminal parameters and thus cause infertility among the treated groups of mice.