Modulation of MDR1 Gene Expression by a Chronic Treatment with Verapamil in Caco-2 Cells

Marilena Granzotto; Cristina Zadro; Ilenia Drigo; Fiora Bartoli; Giuliana Decorti

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Modulation of MDR1 Gene Expression by a Chronic Treatment with Verapamil in Caco-2 Cells

机译：慢性维拉帕米对Caco-2细胞中MDR1基因表达的调节。

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The aim of this study was to investigate the effect of a chronic treatment with low doses of verapamil, as used in cardiovascular therapy, on the expression of mRNAs coding for transport proteins, in cultured Caco-2 cells. Caco-2 cells were selected in vi

机译：这项研究的目的是研究低剂量维拉帕米的慢性治疗（用于心血管治疗）对培养的Caco-2细胞中编码转运蛋白的mRNA表达的影响。在体内选择了Caco-2细胞

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《International Journal of Pharmacology》 |2005年第1期|共8页
作者
Marilena Granzotto; Cristina Zadro; Ilenia Drigo; Fiora Bartoli; Giuliana Decorti;
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中图分类药学;
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1. Multi drug resistance-1 (MDR1) expression in response to chronic diazinon exposure: an in vitro study on Caco-2 cells. [J] . Habibollahi P, Ghahremani MH, Azizi E, Bulletin of Environmental Contamination and Toxicology . 2011,第1期

机译：响应慢性二嗪农暴露的多药耐药性1（MDR1）表达：对Caco-2细胞的体外研究。
2. Multi Drug Resistance-1 (MDR1) Expression in Response to Chronic Diazinon Exposure: An In vitro Study on Caco-2 Cells [J] . Peiman Habibollahi, Mohammad Hossein Ghahremani, Ebrahim Azizi, Bulletin of Environmental Contamination and Toxicology . 2011,第1期

机译：多药耐药-1（MDR1）表达对慢性二嗪农暴露的响应：Caco-2细胞的体外研究
3. Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells. [J] . Donmez Y, Akhmetova L, Iseri OD, Cancer chemotherapy and pharmacology. . 2011,第4期

机译：MDR调节剂维拉帕米和异丙嗪对耐阿霉素的MCF-7细胞中MDR1和MRP1基因表达水平的影响。
4. PREDNISOLONE EXPOSURE FOR THREE DAYS DOES NOT INDUCE MDR1 GENE EXPRESSION IN TWO LYMPHOMA CELL LINES [C] . Bonnie Brugmann, Hollie Lee, Annette Smith, Annual Conference of the Veterinary Cancer Society . 2009

机译：泼尼松龙暴露三天不会诱导两个淋巴瘤细胞系中的MDR1基因表达
5. Transport of ascorbic acid across Caco-2 cell monolayers and its effects on gene expression by large-scale transcriptional profiling. [D] . Chappa, Arvind Kumar. 2003

机译：抗坏血酸跨Caco-2细胞单层的转运及其对基因表达的影响（通过大规模转录谱分析）。
6. Chrysosplenetin inhibits artemisinin efflux in P-gp-over-expressing Caco-2 cells and reverses P-gp/MDR1 mRNA up-regulated expression induced by artemisinin in mouse small intestine [O] . Liping Ma, Shijie Wei, Bei Yang, 2017

机译：Chrysosplenetin抑制过度表达P-gp的Caco-2细胞中的青蒿素外流并逆转由青蒿素诱导的小鼠小肠中P-gp / MDR1 mRNA上调的表达
7. Modulation of MDR1 Gene Expression by a Chronic Treatment with Verapamil in Caco-2 Cells [O] . Marilena Granzotto, Cristina Zadro ., Ilenia Drigo ., 2004

机译：通过Caco-2细胞慢性处理调制MDR1基因表达

Modulation of MDR1 Gene Expression by a Chronic Treatment with Verapamil in Caco-2 Cells

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