Antimicrobial Activity and Chemical Composition of Essential Oil from Pittosporum eugenioides

摘要

Medicinal and aromatic plants (MAPs) have been explored for their essential oil along with the past few decades. Essential oilconsidered as a complex volatile compounds, synthesized naturally in different parts of the plant during the secondary metabolismprocess. The chemical composition and antimicrobial activity of essential oil isolated by hydrodistillation from the aerial partsof Pittosporum eugenioides (Pittosporaceae), were evaluated. The chemical composition was investigated by Gaschromatography/Mass spectrometry (GC-MS). Thirteen volatile components were identifying in essential oil, corresponding to 99 %of the total oil. Essential oil was rich in Butylated hydroxytoluene (58.79%), 5,11,17,23-tetrakis(1,1-dimethylethyl)-28-methoxypentacyclo-[19.3.1.1(3,7).1(9,13)-1(15,19)]octacosa 1(25),3,5,7(28),9,11,-13(27),15,17,19(26),21,23 dodecene-25,26,27-triol (30.73%), Stigmast-5-en-3-ol, (3á,24S)-(CAS) (2.63%) and Mebutamate (2.04%) as the major components most of them arephenolic compounds. The antimicrobial activity was studied by the well diffusion method. The antimicrobial activity was testedagainst six pathogenic microbial strains including Gram +ve (Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus),Gram –ve (Escherichia coli and Salmonella typhimurium) bacteria and fungi (Aspergillus fumigatus and Candida albicans). Theessential oil from P. eugenioides exhibited a very good antimicrobial activity against Aspergillus fumigatus with inhibition zone 14mm compared to Ketoconazole which exhibited inhibition zone 17 mm. These findings will benefit for researchers who wish toexplore essential oil potential in the development of novel broad-spectrum key molecules against a broad range of drug-resistantpathogenic known microbes.