ANTICONVULSANT ACTIVITY OF THE METHANOLIC EXTRACT OF LAWSONIA INERMIS LEAVES IN ALBINO RATS

摘要

The aim of the study was to determine the anticonvulsant activity of methanolic extract of Lawsonia inermis leaves in albino rats. The anticonvulsant activity of methanolic extract of leaves of Lawsonia inermis (200 mg/kg and 400 mg/kg) was assessed in rats using maximum electroshock seizure (MES) test and pentylenetetrazole (PTZ) induced seizure test. The methanolic extract of Lawsonia inermis leaves significantly (pLawsonia inermis has significant anticonvulsant activity possibly through a GABA-ergic interaction