A REVIEW ON GENESIS AND CHARACTERIZATION OF PHYTOSOMES

摘要

The whole plant of Rhus mysorensis of Anacardiaceae family is traditionally used in the treatment of diabetes. The aim of the present study was to evaluate the ethanolic extract of the whole plant of Rhus mysorensis for hepatoprotective effect against carbontetrachloride-induced liver damage in rats. Administration of ethanolic extract of the whole plant of Rhus mysorensis protect the liver from toxic effects of carbontetrachloride by reducing the elevated levels of Serum glutamate pyruvate transaminase (SGPT), Serum glutamate oxaloacetate transaminase (SGOT), serum bilirubin, Serum alkaline phosphatase (SALP). The hepatoprotective activity was also supported by histopathological studies of liver tissue. Since results of biochemical studies of blood samples of carbon tetrachloride treated rats showed significant increase in the levels of serum enzyme activities, reflecting the liver injury caused by CCl4 and blood samples from the animals treated with the ethanolic extract of Rhus mysorensis showed significant decrease in the levels of serum markers, indicating the protection of hepatic cells, the extract of above plant could afford significant protection against CCl4 induced hepatocellular injury.