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首页> 外文期刊>International Journal of Pharmaceutical Sciences Review and Research >Snake Bite, Venom, Anti-Venom Production and Anti-Venom Activity of Medicinal Plants: A Review”
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Snake Bite, Venom, Anti-Venom Production and Anti-Venom Activity of Medicinal Plants: A Review”

机译:药用植物的蛇咬,毒液,抗毒液产生和抗毒液活性:综述”

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The aim of the study is to evaluate the benefit(s) of bacteriophage activity as antibacterial agent alone and in combination(s) with antibiotic(s) against Multidrug Resistant (MDR) S. aureus. Fifty eight samples were collected from patients with multiple types of infections attainted to The Medical City of Al-imamain Al-khadimain (peace being upon them) from February 2014 to April 2014. Combinations of phage with ? and ? MIC of gentamicin, ? and ? MIC of vancomycin and ? and 1 MIC of tetracycline for isolate 4 and combinations of phage with ? MIC of gentamicin, ? MIC of vancomycin and ? and 1 MIC of tetracycline for isolate showed synergistic effects against S. aureus isolates, while combinations of phage with ? MIC of gentamicin and ? MIC of vancomycin for isolate 7 showed indifference effects. Almost all phage-antibiotic combinations resulted in synergism and only two combinations showed indifference effects. It is recommended to study the synergistic effect of antibiotic-combinations and phage-antibiotic combinations in vivo using suitable laboratory animals.
机译:这项研究的目的是评估噬菌体活性作为单独的抗菌剂以及与抗生素联合使用对多药耐药性(MDR)金黄色葡萄球菌的益处。从2014年2月至2014年4月到达Al-imamain Al-khadimain医药城(和平的他们)获得多种感染的患者中,收集了58份样品。和?庆大霉素的MIC ,?和?万古霉素的MIC和?和1 MIC的四环素用于分离物4和噬菌体与β的结合庆大霉素的MIC ,?万古霉素的MIC和? 1 MIC和四环素分离株对金黄色葡萄球菌分离株具有协同作用,而噬菌体与β庆大霉素的MIC和?万古霉素对分离株7的MIC显示出无差异作用。几乎所有噬菌体-抗生素组合均产生协同作用,只有两种组合显示出无差异的效果。建议使用合适的实验动物在体内研究抗生素组合和噬菌体-抗生素组合的协同作用。

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