SYNTHESIS, CHARACTERIZATION, THERMAL AND KINETIC STUDIES OF LANTHANUM (III), THORIUM (IV) AND DIOXOURANIUM (VI) CHELATES WITH MULTIDENTATE LIGAND AND ITS IN VITRO ANTIBACTERIAL ANALYSIS

摘要

Metal Complexes of lanthanum (III), Thorium (IV) and dioxouranium (VI) with Schiff base ligand ethyl 2-{[(2E, 3Z)-4-hydroxypent-3-en-2-ylidene] amino}-4, 5, 6, 7-tetrahydro-1-benzothio-phene-3-carboxylate were prepared. All synthesized complexes were identified and confirmed by elemental analysis, molar conductance measurements and spectral analysis (UV-visible, IR and 1H NMR). The conductance measurement suggested the non-electrolyte nature of the complexes and they were isolated in 1:2 (M: L) ratio. The thermal behavior (TGA/DTA) of the complexes was studied and kinetic parameter was determined by Coats-Redfern method. The data from thermo gravimetric analysis clearly indicates that decomposition of the complexes proceeds in two or three steps .The decomposition of all the complexes ended with the metal oxide. These metal complexes also showed its potential as an antibacterial agent against pathogenic strains causing urinary tract infections.