CORRELATION BETWEEN URINARY MICROALBUMIN, GLYCOSYLATED HAEMOGLOBIN AND SERUM MAGNESIUM IN TYPE 2 DIABETIC PATIENTS

摘要

Background & objectives: – Diabetes mellitus comprises a group of common metabolic disorders that share the phenotype of hyperglycemia. One of the leading causes of diabetes mellitus related morbidity and mortality is diabetic nephropathy. The earliest stage of diabetic nephropathy is Microalbuminuria, which is the excretion of extremely small quantities of albumin in the range of 30 – 300 mg/day. Hypomagnesaemia may be a risk factor for progression of complications in type 2 diabetes mellitus. Material & methods: -The material for the present study comprised of 60 patients of type2 diabetes mellitus. Glycosylated hemoglobin, serum magnesium and urinary microalbumin were measured. Results: – It was found that the glycemic control as indicated by glycosylated hemoglobin is related significantly to microalbuminuria. Poor glycemic control leading to renal damage causes microalbuminuria. A significant inverse correlation between serum magnesium and urinary microalbumin levels was also observed. Conclusion: – Estimation of urinary microalbumin, glycosylated haemoglobin and serum magnesium should be routinely done in confirmed cases of type 2diabetes mellitus.