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Respiratory Effects Induced by Occupational Exposure to Formaldehyde among Health Care staff

机译:卫生保健人员职业接触甲醛引起的呼吸作用

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Formaldehyde is a common indoor pollutant with irritant properties. The present case control study was undertaken among 37 exposed staff with formaldehyde and 19 non exposed (referent) ones to study the acute and chronic effects of it in two educational hospitals. All subjects were tested for respiratory function by a portable alpha Vitalograph-UK. In addition using a respiratory questionnaire, data on demographic information and respiratory symptoms were collected. The results showed that exposed medical staff had high prevalence rates of regular cough, wheezing and itching and burning sensations of the nose on acute exposure to formaldehyde. These effects were higher on chronic exposure. On the other hand, although the respiratory function parameters such as FVC (Forced Vital Capacity), FEV1 (Volume that has been exhaled at the end of the first second of forced expiration) and PEF (The highest forced expiratory flow measured with a peak flow meter) diminished in some exposed subjects, the respiratory function in two groups of subjects did not indicate any significant differences ( p < 0.05). In conclusion the respiratory function test cannot be always exact criteria to demonstrate adverse health effect of formaldehyde exposure.
机译:甲醛是一种常见的具有刺激性的室内污染物。本病例对照研究是在37名暴露于甲醛的工作人员和19名未暴露(相关)人员中进行的,以研究其在两家教育医院中的急性和慢性作用。所有受试者均通过便携式alpha Vitalograph-UK进行了呼吸功能测试。除了使用呼吸问卷之外,还收集了有关人口统计学信息和呼吸症状的数据。结果表明,暴露于医务人员的急性甲醛接触率很高,经常咳嗽,喘息,瘙痒和鼻子灼热感。这些对慢性接触的影响较高。另一方面,尽管呼吸功能参数包括FVC(强制肺活量),FEV1(在强制呼气的第一秒结束时呼出的容积)和PEF(以峰值流量测量的最高强制呼气流量)在一些暴露的受试者中,呼吸机功能降低),两组受试者的呼吸功能未显示任何显着差异(p <0.05)。总之,呼吸功能测试不能总是精确的标准来证明甲醛暴露对健康的不利影响。

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