Noninvasive measurement of relative blood oxygen saturation in human retina by using 1μm Fourier Domain Optical Coherence Tomography

摘要

The relative blood oxygen saturation measurement has been done in human retina by using Fourier Domain Optical Coherence Tomography (FDOCT) data. A broadband (120 nm bandwidth) light source with central wavelength, 1060 nm was used in FDOCT for deeper penetration in retina. A least squares method was implemented to extract oxy and de-oxy haemoglobin concentrations from the FDOCT data. The measured blood oxygen saturation levels in an artery and veins are comparable with existing methods. Thus, this technique can be used to measure in-vivo relative blood oxygen saturation non-invasive way.