Evaluation of Parenteral Nutrition Therapy in Patients Undergoing HSCT

摘要

Introduction: Parenteral nutrition (PN) therapy remains an essential part of patients’ care during HSCT. There are many studies that focused on nutrition therapy in this population study, but there is not any consensus statement about nutrition therapy in patients who are hospitalized for bone marrow transplantation. The aim of the present study was to assess PN status and related complications in the patients during the course of HSCT in the HSCT wards of a referral teaching hospital. This study was conducted in the three HSCT wards of Shariati Hospital, Tehran, Iran. Methods: During a prospective study, data related to PN therapy were collected by clinical pharmacist during six-month period. PN therapy information including PN initiation, PN content, PN duration, and total daily calories intake in comparison with standard calories intake was recorded for each patient. An internal protocol for PN therapy was designed based on reliable guideline. The data related to patients’ nutrition therapy were compared with this protocol. The nutrition therapy was considered appropriate if it was compatible with the protocol regarding time of PN initiation, PN content , rout of PN administration, PN duration, and total kilocalories received. Result: The average of duration of hospital stay and PN therapy were 27.17± 9.16 and 15 ± 6.1 days respectively.One hundred and fifty-seven of medication errors were detected during the study period in the patients. Overall rate of PN therapy errors was 2.3 numbers per patient during hospitalization. Errors in the rate of errors in the content of PN administration (100%) and incorrect total daily calories intake (55.9%), incorrect PN initiation (54%) and incorrect PN duration (25.6%) were the most common types of PN therapy. Conclusion: Our result showed that inappropriate PN therapy occurred commonly in the patients undergoing HSCT. Improvement in knowledge and attention of health-care workers about nutrition support for preventing of malnutrition in aspect of nutrition therapy.