There have been relatively few opportunities to examine the cardiovascular effects of an extreme air pollution event in China. We aimed to examine the impact of the 2013 Eastern China Smog occurring from 2 to 9 December 2013, on outpatient visits for coronary heart diseases (CHD) in a typical hospital in Shanghai, China. We used the over-dispersed, generalized additive model to estimate the relative risk (RR) of the 2013 Eastern China Smog on the outpatient visits by comparing the smog period (2–9 December 2013; 8 days) to the non-smog period (1 November–1 December 2013, and 10 December–28 February 2014; 112 days). This model also controlled for time trends, days of the week, holidays, and meteorological factors. A stratification analysis was performed to estimate sex- and age-specific RRs. The daily average PM 2.5 (fine particulate matter with an aerodynamic diameter less than 2.5 μm) concentrations during the smog period were 212 μg/m 3 , which were three times higher than during the non-smog period (76 μg/m 3 ). The smog in Eastern China in 2013 was significantly associated with an increased risk of outpatient visits for CHD. For example, the RR was 1.18 (95% CI: 1.04, 1.32) on lag 0 day. There were similar effects on males and females. Our analyses provided preliminary evidence that smog constituted a significant risk factor of CHD in China.
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机译：在中国，检查极端空气污染事件对心血管的影响的机会相对较少。我们旨在研究2013年12月2日至9日发生的2013年华东烟雾事件对中国上海一家典型医院的冠心病（CHD）门诊病人的影响。通过比较雾霾期（2013年12月2日至9日; 8天）与非雾霾期（2013年12月2日至9日），我们使用过度分散的广义加性模型估算了2013年华东地区雾霾的相对风险（RR） 2013年11月1日至12月1日，以及2014年12月10日至2月28日; 112天）。该模型还控制了时间趋势，星期几，节假日和气象因素。进行分层分析以估计特定性别和特定年龄的RR。烟雾期间的每日平均PM 2.5（空气动力学直径小于2.5μm的细颗粒物）浓度为212μg/ m 3，是非烟雾时期（76μg/ m 3）的三倍。 2013年，华东地区的烟雾与冠心病门诊的风险增加显着相关。例如，滞后0天的RR为1.18（95％CI：1.04，1.32）。对男性和女性也有类似的影响。我们的分析提供了初步证据，证明烟雾是中国冠心病的重要危险因素。
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