Simultaneous Determination of Clenbuterol and Salbutamol with a Graphene-Nafion Nanocomposite Modified Electrode

摘要

A highly sensitive electrochemical sensor for the simultaneous determination of clenbuterol (CLB) andsalbutamol (SAL) was fabricated by the modification of graphene-Nafion (GN-Nafion) composite filmon a glassy carbon electrode (GCE). Both CLB and SAL caused a pair of redox peaks at the GN- Nafion/GCE in 0.04 M Britton-Robinson buffer solution. Obvious anodic peak currents for theoxidation of both CLB and SAL were observed under the optimal condition. The difference ofoxidation peak potentials for CLB and SAL was about 200 mV, which made it possible forsimultaneous determination of these compounds using the GN-Nafion/GCE. The detection limit forCLB and SAL was 0.13 M and 0.11 M (S/N=3), respectively. The proposed method was applied tosimultaneously detect CLB and SAL in pork meat with satisfactory results. Otherwise, the excellentreproducibility, stability and selectivity were obtained at the proposed electrode.