Covalent Functionalized Carbon Nanotube with Ionic Liquid and Its Application for Human Immunoglobulin G Immunosensor

摘要

In this work, ionic liquid functionalized carbon nanotube was simply prepared via covalent bond betweenaldehyde-terminated ionic liquid and amino-terminated carbon nanotube. The combination overcamethe shortages and shared the advantages of both ionic liquids and carbon nanotube. On the one hand,ionic liquid was prevented to leach out from electrode surface to electrolyte solution, which resulting astable sensing interface. In the meantime, the degree of curling of CNT was decreased. On the otherhand, this novel hybrid nanomaterial can further improve the conductivity of film modified on theelectrode surface. The prepared immunosensor was used to detect human IgG in a linear range of 0.1-15 ng mL -1 . The detection limit was 0.02 ng mL -1 (S/N=3). The electrochemical immunosensor with filmfabricated with the hybrid nanomaterial had satisfactory reproducibility, high sensitivity, acceptablespecificity and good stability.