Development of a Semiconductor-Based Electrochemical Sensor for Interferon-γ Detection

摘要

This report described an excellent method for interferon gamma (IFNγ) detection using a label-free electrochemical impedance immunosensor. TiO2 NPs prepared using a simple hydrothermal strategy were applied to the immobilization of the IFNγ monoclonal antibody. The relative increase in the impedance value was proportional to the logarithmic value of the IFNγ concentration (0.001 - 0.2 ng/mL), and the limit of detection (LOD) was calculated as 0.74 pg/mL. This work presented a facile, novel and highly sensitive strategy.