Distance complexity analysis of DNA Nucleotide Sequence with Normal and Cancer Liver Cells Using Data Mining Techniques

摘要

The proposed work focuses on Hidden Markov Model (HMM), has increased on the Pattern recognition domain primarily because of its strong mathematical basis and the ability to adapt to unknown of nucleotide sequence of normal and cancer affected liver cells as are pictorially represented by finite state machine. The proposed methodology will focused and analyzed about performance of DNA gene liver cancer database and normal liver cell data set from ncbi DNA data set. After analyzing the cancer cells, there is a need to determine the distance between normal and cancer affected cells. Each amino acid can have character variables and also assigned numeric number and its corresponding pair combination of sequence are represented in a graph. The proposed HMM system is validated with two different nucleotide values for analyse the performance and get the simulated output using viterbi and forward algorithms implemented in Mat Lab Tool.