Bioinformatics in Stem Cell Characterization

摘要

Speaking in realistic sense a stem cell is endowed with potentials only, which are options rather than specific gene-expression patterns, thereby making its identification vague. Their characterization thus necessitates an overall genomic and proteomic analysis, coupled with mathematical modeling providing for the need for a wide range of bioinformatics tools to efficiently and effectively process large amounts of data being generated. A large number of computational tools and bioinformatic methods are thus required to deal with the experimental riches of this complex and multivariate data and the subsequent transition from data collection to information or knowledge in order to arrive at a universal definition of stemness.