Large Cell Neuroendocrine Carcinoma of the Ovary Associated with Serous Carcinoma with Mucin Production: A Case Report and Literature Review

摘要

Large cell neuroendocrine carcinoma (LCNEC) of the ovary is a rare entity and is frequently associated with ovarian surface epithelial tumors. However, its association with serous carcinoma has only been described recently in one case. We report another case of such with mucin production in a 68-year old woman. Immunohistochemistry and mucicarmine stain confirmed the diagnosis. Its clinicopathologic association is discussed and the literature is reviewed.