Antibacterial activities of Myrtus communis L extract against Multi-Drug resistant Klebsiella pneumonia and Pseudomonas aeruginosa

摘要

In this study the antibacterial activities of Myrtus communis L. extract against Multi-Drug resistant Klebsiella pneumoniaand Pseudomonas aeruginosathat isolates from the urinary tract infection by microtiterplate method are studied. All 12 strains of Klebsiella pneumoniaeand Pseudomonas aeruginosaisolated from urine culture of hospitalized patients (Amir Al-Momenin Hospital, Zabol, south-eastern Iran) suffered from urinary tract infections during the years 2011-2012. In this study, the extract of Myrtus communis Lobtained by rotary and the minimum inhibitory concentrations were investigated to characterize the antimicrobial activities of this extract.Overall, k. pneumoniaewas resistance to 3 of the agent including ceftazidime(33.3%), cefixime(58.3%), erythromycin(75%) and P. aeruginosawas resistance to 4 antibiotic that included ceftazidime(33.3%), tobramycin(8.3%), piperacillin(8.3%) and cefixime(83.3%). The highestMIC values of extract was found to be 20mg/ml against K.pneumoniaeandten of MIC value for K.pneumoniaewas 10mg/ml and the highestMIC values of extract was found to be 20mg/ml againts P. aeruginosaandeight of MIC value for Pseudomonas aeruginosawas 10mg/ml. These results suggest that M. communisLleaves may be utilized as a potential source of bactericidal, but in vivostudies are required to support this.