The impact of cobalt chloride on enzyme activity of mice

摘要

Liver is a primary site of toxic and plays important role metabolism, any changes in cobalt concentration in blood; this may affect the activities of antioxidant enzymes for adult male mice. (80) Days old, weighing 30- 35 gm., were treated orally COCl2 (15, 30, 45) mg / kg Body weight for 30 days. The acid phosphatase, alkaline phosphatase in the plasma and liver were estimated. There was a significant increasing in the activity of enzyme (p0.05), these enzyme with moderate and high dose (30, 45) while no change with low dose (15). This investigation concluded that COClSUB2/SUB caused increasing in the levels of enzyme with increase of dose.