ANTIBACTERIAL ACTIVITY OF ESSENTIAL OIL OF SYZYGIUM AROMATICUM (L.) MERR.PERRY (CLOVES) AGAINST CLINICAL ISOLATES OF AGGREGATIBACTER ACTINOMYCETEMCOMITANS

摘要

Aim: Aggregatibacter actinomycetemcomitans implicated in the etiology of aggressive, chronic periodontitis and other systemic infections. The aim of this study was to investigate the antibacterial efficacy of essential oil of a traditional medicinal plant, Syzygium aromaticum (L.) Merr.perry (cloves) against the clinical isolates of A.actinomycetemcomitans obtained from the patients with orodental infections. Methodology: Essential oil of clove flower buds was distilled by Neo-Clevenger's method and the antibacterial activity was tested by disc diffusion and agar punch well method. The minimum inhibitory concentration of clove oil was determined by micro broth dilution method. Results: 80.8% of the isolates showed sensitivity against clove oil by disc diffusion technique and the minimum inhibitory concentration of clove oil was ranged between 3.125μl/ml to 12.5μl/ml. Conclusion: Essential oil of Syzygium aromaticum showed good antibacterial activity and can be considered as alternative treatment option for control of periodontitis and other orodental infections caused by A.actinomycetemcomitans.