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Effect of Asmarihara kasaya curna (ASM)-an ayurvedic formulation on lipid profile after chronic administration

机译:阿育吠陀药草(ASM)-阿育吠陀制剂对慢性给药后脂质分布的影响

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Asmarihara Kasaya Curna (ASM), a classical Ayurvedic preparation which is widely used in Urolithiasis .The research was carried out in order to observe the effect of this formulation on lipid profile reveals that it possesses hypotriglyceridemic property after chronic administration for 45 consecutive days. In the male rats there was a statistically very highly significant decrease in the Triglycerides (p=0.001***) content in the plasma. On the contrary an increase in the Total Cholesterol (p=0.285NS), VLDL (p=0.173 NS) and LDL (p=0.023*) content in the plasma was noted. There was an insignificant decrease (p=0.771 NS) in HDL. In the female rats there was a statistically very highly significant decrease in the Triglycerides, content (p=0.001***) in the plasma. Interestingly none of the other changes in case of the total Cholesterol (p=0.924 NS), VLDL (p=0.329 NS), LDL (p=0.881 NS) and HDL (p=0.983 NS) were significantly different from their corresponding control values. But in male rats, the content of the LDL in plasma a statistically significant increase was noted which was different from female rats.
机译:Asmarihara Kasaya Curna(ASM)是一种广泛用于泌尿系统结石的经典阿育吠陀制剂。为了观察该制剂对脂质分布的影响,进行了研究,结果表明该制剂在连续服用45天后具有降甘油三脂的特性。在雄性大鼠中,血浆中甘油三酸酯含量有统计学上非常显着的下降(p = 0.001 ***)。相反,注意到血浆中总胆固醇(p = 0.285NS),VLDL(p = 0.173 NS)和LDL(p = 0.023 *)含量增加。 HDL的减少无统计学意义(p = 0.771 NS)。在雌性大鼠中,血浆甘油三酸酯含量(p = 0.001 ***)在统计学上非常显着降低。有趣的是,总胆固醇(p = 0.924 NS),VLDL(p = 0.329 NS),LDL(p = 0.881 NS)和HDL(p = 0.983 NS)的其他变化均与相应的对照值没有显着差异。但是在雄性大鼠中,血浆中LDL的含量有统计学上的显着增加,这与雌性大鼠不同。

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