POTENTIAL EFFECT OF CALCIUM CHLORIDE (CaCl₂) AS CHEMICAL CASTRATIVE AGENT ON MALE ALBINO RAT

摘要

Present study deals with the efficiency of calcium chloride (CaCl 2 ) as chemical castrative agent. Intratesticular injection of CaCl 2 has been given to the animals of two experimental groups in different doses. After completion of 30 days, animals were sacrificed. There was no significant difference of weight gain between control and experimental animals but the weight of testis and epididymis was significantly reduced. Reduction of sperm count and sperm motility was also significant in experimental animals compare to that of their respective control. SGPT and SGOT were measured as metabolic marker and were found insignificant between control and experimental animal groups. Some changes were also observed in histological structure of testis of experimental animals compare to the histological structure of control animal showing hampered structural organization of testicular characteristics.