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Application environmental epidemiology to vehicular air pollution and health effects research

机译:环境流行病学在车辆空气污染和健康影响研究中的应用

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Vehicular pollution is one of the major contributors to the air pollution in urban areas and perhaps and accounts for the major share of anthropogenic green-house gases such as carbon dioxide, carbon monoxide, nitrogen oxides. Knowledge of human health risks related to environmental exposure to vehicular pollution is a current concern. Analyze the range health effects are attributed varied constituents of vehicular air pollution examine evidence for a causal association to specific health effect. In many instances scenario involves exposure to very low doses of putative agents for extended periods, sometimes the period could mean over a lifetime of an individual and yet may result in small increase in health risk that may be imperceptible. Secondary data analysis and literature review. In environmental exposures, traditional epidemiological approaches evaluating mortality and morbidity indicators display many limiting factors such as nonspecificity of biological effects latency time between exposure and magnitude of the effect. Long latency period between exposure and resultant disease, principally for carcinogenic effects and limitation of epidemiological studies for detecting small risk increments. The present paper discusses the methodological challenges in studying vehicular epidemiology and highlights issues that affect the validity of epidemiological studies in vehicular pollution.Keywords: Environmental epidemiology, health effects, vehicular pollution
机译:车辆污染是造成城市地区空气污染的主要因素之一,也许占人为温室气体(例如二氧化碳,一氧化碳,氮氧化物)的主要份额。当前对与环境暴露于车辆污染有关的人类健康风险的了解。分析范围健康影响归因于车辆空气污染的各种成分,检查与特定健康影响有因果关系的证据。在许多情况下,情况涉及长时间暴露于极低剂量的推定药物中,有时该时期可能意味着一个人的一生,但可能导致健康风险的小幅增加,这是难以察觉的。二级数据分析和文献综述。在环境暴露中,评估死亡率和发病率指标的传统流行病学方法显示出许多限制因素,例如生物学效应的非特异性以及暴露与效应强度之间的潜伏时间。暴露与导致疾病之间的潜伏期长,主要是由于致癌作用和流行病学研究的局限性,无法检测到小风险增加。本文讨论了研究车辆流行病学的方法学挑战,并重点介绍了影响流行病学研究在车辆污染中的有效性的问题。关键词:环境流行病学,健康影响,车辆污染

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