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A multicenter point-prevalence study: antimicrobial prescription frequencies in hospitalized patients in turkey

机译:多中心点患病率研究:土耳其住院患者的抗菌药物处方频率

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Background Accurate information about prescribing patterns in hospitals is valuable in improving the quality of antimicrobial prescriptions. Methods Data on the use of antimicrobial agents in eighteen tertiary care hospitals were collected on March 20th 2002. Results One or more antimicrobials were ordered in 2900 (30.6 %)of 9471 hospitalized patients. The reasons of hospitalization of the patients receiving antimicrobials were medical treatment (42.5 %), elective surgery (39.6 %), treatment of infectious disease (17.1 %) and emergent surgical procedures (10.4 %). The highest consumption frequencies were found in surgical (81.6 %) and medical (55.2 %) intensive care units. The 48.8 % of antimicrobials were given for treatment and 44.2 % for prophylactic use. The most common reasons for treatment were found as lower respiratory tract, urinary tract, surgical wound infections and febrile neutropenia. Antimicrobials were ordered empirically in 78.4 % of patients. The proven infection ratio was found as 30.7 %. The 56.4 % and 13.4 % of orders were evaluated as clinically and microbiologically appropriate respectively. Conclusion These results suggest that antimicrobial prescription and empirical treatment ratios were high and inappropriate at inpatient groups.
机译:背景技术关于医院处方方式的准确信息对于提高抗菌药物处方的质量非常重要。方法于2002年3月20日收集了18家三级医院的抗菌药物使用数据。结果在9471例住院患者中,有2900例(30.6%)订购了一种或多种抗菌药物。接受抗生素治疗的患者住院原因为药物治疗(42.5%),择期手术(39.6%),传染病治疗(17.1%)和紧急手术程序(10.4%)。在外科(81.6%)和医疗(55.2%)的重症监护室中发现最高的消耗频率。给予了48.8%的抗微生物剂用于治疗,预防性使用了44.2%。治疗的最常见原因是下呼吸道,泌尿道,手术伤口感染和发热性中性粒细胞减少。 78.4%的患者凭经验订购了抗菌药物。证实感染率​​为30.7%。分别对56.4%和13.4%的订单进行了临床和微生物学评估。结论这些结果表明,住院患者的抗菌药物处方和经验治疗比率较高且不合适。

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