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Neurobrucellosis presenting as an intra-medullary spinal cord abscess

机译:神经布鲁菌病表现为髓内脊髓脓肿

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Background Of the diverse presentation of neurobrucellosis, intra-medullary spinal cord abscess is extremely rare. Only four other cases have been reported so far. We present a case of spinal cord intra-medullary abscess due to Brucella melitensis. Case presentation A forty-year-old female presented with progressive weakness of both lower limb with urinary incontinence of 6 months duration. She was febrile. Neurological examination revealed flaccid areflexic paraplegia with T10 below sensory impairment including perianal region. An intramedullary mass was diagnosed on Magnetic Resonance Image (MRI) scan extending from T12 to L2. At surgery, a large abscess was encountered at the conus medullaris, from which Brucella melitensis was grown on culture. She was started on streptomycin and doxycycline for 1 month, followed by rifampicin and doxycycline for 1 month. At 2-year follow-up, she had recovered only partially and continued to have impaired bladder function. Conclusion Neurobrucellosis, if not treated early, can result in severe neurological morbidity and sequale, which may be irreversible. Hence it is important to consider the possibility of neurobrucellosis in endemic region and treat aggressively.
机译:背景在神经布鲁菌病的多种表现中,髓内脊髓脓肿极为罕见。迄今为止,仅报告了另外四例。我们提出一例因布鲁氏布鲁氏菌引起的脊髓髓内脓肿。病例介绍一名40岁女性,下肢双侧无力,尿失禁持续6个月。她很热。神经系统检查显示松弛性反射性截瘫,T 10 低于感觉障碍,包括肛周区域。通过磁共振成像(MRI)扫描诊断出髓内肿块,从T 12 到L 2 。手术时,在髓质圆锥体上遇到了巨大的脓肿,从中培养布鲁氏菌。她开始接受链霉素和强力霉素治疗1个月,随后接受利福平和强力霉素治疗1个月。在2年的随访中,她仅部分恢复,并继续患有膀胱功能受损。结论神经布鲁菌病如果不及早治疗,会导致严重的神经系统疾病和后​​遗症,可能是不可逆的。因此,重要的是要考虑流行地区神经布鲁氏菌病的可能性并积极治疗。

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