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A descriptive study to analyze chemotherapy-induced hair loss and its psychosocial impact in adults: Our experience from a tertiary care hospital

机译:描述性研究可分析化学疗法引起的脱发及其对成年人的社会心理影响:我们在三级医院的经验

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Background: Hair loss is one of the most commonly reported and psychologically distressing adverse effects of chemotherapeutic agents. Studies on its impact on psychosocial aspect of cancer patients are lacking at present. Objective: To study the chemotherapeutic agents causing hair loss and its psychosocial implications in adults. Materials and Methods: Observational study was done for a period of 1 year, wherein all cancer patients, more than 18 years of age who developed hair loss while on chemotherapy were assessed for type of malignancy, details of chemotherapy protocol, their knowledge about chemotherapeutic agents induced hair loss, and its impact on their social life and patterns of adjustment to deal with it. A prevalidated closed-ended questionnaire was used as a data collection tool. Results: Out of 179 patients, 96 (53.6%) were males as against 80 (44.6%) females, and 49 (27.3%) patients were between 18 and 30 years of age. Carcinoma lung was the most common malignancy seen in 46 (25.6%) patients followed by rectosigmoid carcinoma in 41 (22.9%) patients. Combination of cyclophosphamide and doxorubicin was the most common combination resulting in hair loss in 49 (27.3%) cancer patients. A total of 101 (56.4%) patients felt that hair loss was the worst side effect of chemotherapy, while 29 (16.2%) had to continue because it was life-saving. A total of 129 (72%) patients said hair loss is affecting their social life; 37 (20.6%) patients were using hair accessories while 69 (38.5%) did not even attempt to hide hair loss as they were too occupied with fear of disease. Conclusion: Chemotherapy-induced hair loss is a common adverse effect in cancer patients undergoing treatment. A thorough counseling about it and methods to deal with it should be a part of management of the patients.
机译:背景:脱发是化学治疗药物中最普遍报道且在心理上令人困扰的不良反应之一。目前尚缺乏对癌症患者心理社会方面影响的研究。目的:研究导致成年人脱发的化学治疗剂及其心理社会意义。材料和方法:进行了为期1年的观察性研究,其中评估了所有18岁以上在化疗时脱发的癌症患者的恶性类型,化疗方案的详细信息以及他们对化疗药物的了解导致脱发及其对他们的社会生活的影响和应对方式。预先验证的封闭式调查表用作数据收集工具。结果:在179例患者中,男性96例(53.6%),女性80例(44.6%),年龄在18至30岁之间的49例(27.3%)。肺癌是最常见的恶性肿瘤,占46(25.6%)位患者,其次是直肠乙状结肠癌,占41(22.9%)位患者。环磷酰胺和阿霉素的组合是最常见的组合,导致49名(27.3%)癌症患者脱发。共有101名患者(56.4%)认为脱发是化学疗法的最严重副作用,而29名患者(16.2%)由于必须挽救生命而不得不继续治疗。共有129名患者(72%)说脱发正在影响他们的社交生活; 37(20.6%)名患者在使用发饰,而69名(38.5%)甚至没有试图掩饰脱发,因为他们太担心疾病了。结论:化疗引起的脱发是癌症患者接受治疗的常见不良反应。对其进行彻底的咨询以及应对方法应成为患者管理的一部分。

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