Effect of hypercholesterolemia on fatty infiltration and the quality of tendon-to-bone healing in a rabbit model of a chronic rotator cuff tear: Electrophysiological, biomechanical, and histological analyses

摘要

Background: The incidence of healing failure after rotator cuff repair is high, and fatty infiltration is a crucial factor in healing failure. The purpose of this study was to verify the effect of hypercholesterolemia on fatty infiltration and the quality of tendon-to-bone healing and its reversibility by lowering the cholesterol level in a chronic tear model using the rabbit supraspinatus.