Cartilage storage at 4°C with regular culture medium replacement benefits chondrocyte viability of osteochondral grafts in vitro

摘要

Background: Transplantation using fresh osteochondral grafts is a routine clinical treatment approach resulting in excellent chondrocyte viability and good clinical results. Research has been conducted to establish novel methods to maintain the viability of cartilage grafts for as long as possible in vitro. However, short storage times with reduced cell viability of osteochondral grafts remains an issue in clinical transplantation.