An intraerythrocytic protozoon of genus Babesia causes human babesiosis, earlier known as “Nantucket fever”. The incidence of babesiosis is steadily increasing across the Northeast and upper Midwest United States [1]. Most infections are asymptomatic, although older and immunocompromised persons can develop severe and fatal disease. In addition, the clinical presentation can vary substantially posing diagnostic challenges for the clinician. Splenic infarction, a known complication with plasmodium infection, has only rarely been described with human babesiosis [2]. Here we describe a case of severe babesiosis leading to infarction of the spleen.
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