Advances in understanding and clinical application of memory updating through reconsolidation in humans

摘要

Inactivation of fear engram neurons dur- ing retrieval erased contextual fear memory, perhaps, by blocking memory reconsolidation, whereas activation of these engrams dur- ing retrieval blocked acquisition and consolidation of fear memory extinction. These results suggest that modulation of fear memory engram cells are crucial processes to determine the fate of memory, reconsolidation or extinction.