O efeito da vitamina D nas fun??es cognitivas em pacientes jovens do sexo feminino: um estudo prospectivo controlado usando a avalia??o cognitiva de Montreal

摘要

Aim: Our aim was to determine whether there is a relationship between vitamin D [25(OH)D] and cognitive functioning in women with low 25(OH)D levels. Methods: Ninety female patients, 25-45 years of age, who attended our outpatient clinic and had 25(OH)D levels 30 ng/mL, were included. The Montreal Cognitive Assessment (MoCA) scale was used to determine cognitive functioning; the scale is divided into seven subgroups. Patients were divided into three subgroups according to their 25(OH)D levels. After a three-month period of 25(OH) D replacement, the patients underwent a re-evaluation using the MoCA scale. Results: The total MoCA score before treatment was significantly different from the score after treatment (p 0.05). Language and delayed recall functions were significantly different before and after treatment (p 0.05). Conclusion: Vitamin D levels were related to cognitive functioning in our study group.