Objective: The main objective of this study was to evaluate the factors predicting recurrence in patients who underwent radical prostatectomy (RP) for localized prostate cancer. Materials and Methods: A total of 275 patients who underwent RP between 2000 and 2012 years in our clinic were evaluated retrospectively and 238 patients who met our criteria were included in the study. The effect of PSA values at diagnosis in addition the histopathological variables on the risk of recurrence was evaluated. Biochemical recurrence (BCR) is defined as “an increase of > 0.2 ng/ml or more in the serum total PSA count”. The statistical analysis of this study was done using SPSS for Windows Version 15.0 package program. Values below p 10 ng/ml and Gleason score > 7 are considered as the risk factors for BCR. Conclusion: Our study results showed that PSA value during initial diagnosis as well as Gleason score were independent factors in predicting BCR following radical prostatectomy.
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机译：目的：本研究的主要目的是评估局部前列腺癌行根治性前列腺切除术（RP）患者的复发预测因素。资料与方法：回顾性评估了2000年至2012年间在我们诊所接受RP的275例患者，符合研究标准的238例患者被纳入研究。评估了PSA值对诊断的影响以及组织病理学变量对复发风险的影响。生化复发（BCR）定义为“血清总PSA计数增加> 0.2 ng / ml或更多”。这项研究的统计分析是使用SPSS Windows版本15.0程序包进行的。低于p 10 ng / ml且Gleason评分> 7的值被认为是BCR的危险因素。结论：我们的研究结果表明，初步诊断期间的PSA值以及Gleason评分是预测前列腺癌根治术后BCR的独立因素。
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