The main object of this research work is to develop and studying the stability analysis of orodispersible tablet of piroxicam. Five formulations of orodispersible tablets of piroxicam (F1-F4) were prepared using two different superdisintegrants namely crospovidone and sodium starch glycolate with two concentrations and a control F5 (without superdisintegrant) by direct term stability studies for the formulations showed no significant changes in disintegration compression method. The precompression and post compression study of piroxicam and excipient were carried out. The short time, drug content and percentage of drug released when stored at 4°C±2°C, 27°C ±2°C, and 45°C±2°C for 15 days.
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