DESIGN AND EVALUATION OF NOVEL TOPICAL GEL OF TINOSPORA CORDIFOLIA AS ANTIMICROBIAL AGENT

摘要

Objective: The present study deals with topical formulations of a bioactive extract of Tinospora cordifolia and its evaluation.Methods: Dried, powdered stem was extracted with chloroform using ultra-sonication method for 3 hrs. Topical formulations like gels containingchloroform extract were formulated using various gelling agents. These gels were evaluated for physicochemical parameters, viscosity, spreadaibility,and antimicrobial activity.Results: A topical gel was successfully formulated containing bioactive chloroform extract of T. cordifolia. The gel was very effective as antimicrobialformulations.Conclusion: These kinds of formulations can be very promising wound healing medicines with ease of use and no side effects.