COMPARATIVE STUDY ON ACTIVITIES OF ANTI BACILLARY DYSENTRY SHIGELLA DYSENTERIAE OF SYZYGIUM POLYANTHUM AND DRACAENA ANGUSTIFOLIA LEAVES ETHANOL EXTRACTS

摘要

Bacillary dysentery is an intestinal infection caused by the bacterium Shigella dysenteriae. Complications that often arise in bacillary dysentery is dehydration causing the body to lose a lot of water with salts, especially potassium, causing hypokalemia and the risk of death. This study aims to determine the antibacterial activity of ethanol extract of bay ( Syzygium polyanthum W.) and suji ( Dracaena angustifolia Roxb.) leaves against Shigella dysenteriae and the amount of potassium to the discovery of anti-dysentry drug candidates. Testing activities and comparative value activities performed by the agar diffusion method, whereas the determination of Minimum Kill Concentration (MBC) was done with the subculture media incubation test followed wiith microdilution method on MHA medium sterile. Potassium levels of the extract was carried out quantitatively using AAS. The test results showed that the ethanol extract of both leaves had antibacterial activity against S.dysenteriae with MBC values were in the range of 10-20% w/v. Value comparative effectiveness suji leaf ethanol extract to the bay leaf was 1: 0.4. Potassium levels ethanol extract of bay and suji leaves were 1.027% and 3.795%, respectively. Keywords: bay leaves, suji leaves, Shigella dysenteriae , Potassium, Atomic absorption spectrophotometry.