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Rates of colorectal cancer detection in screening colonoscopy post appendicectomy in patients 50 years and over

机译:50岁及以上患者阑尾切除术后结肠镜检查中大肠癌的检出率

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IntroductionAcute appendicitis in older adults is relatively uncommon and could be the first presentation of an underlying colorectal carcinoma. Colonoscopy in these individuals affords the opportunity for earlier diagnosis and treatment. The finding of increased rates of colorectal cancer (CRC) with older patients who have had appendicitis was supported by a number of small studies and case reports in the early 1980s.With the advent of CT scanning and laparoscopic appendicectomy, increased ability to visualize the caecum has been achieved.PurposeA retrospective 12-month study of all patients presenting with acute appendicitis aged 50 years and over from 1st May 2017 to 31st May 2018, and review of post operative screening colonoscopy findings.ResultsForty-three patients met inclusion criteria. The patients’ median age was 62 years (range 50–85 years). 47% of the patients were male. 86% of patients had abdominal CT scans prior to surgery with acute appendicitis visualized in 97% of these cases. Acute appendicitis was found in 100% of cases with no clinical suggestion of CRC operatively or pathologically. 46% of patients had pertinent findings on colonoscopy. This included a malignant obstructing tumour at the hepatic flexure and a tubular adenoma in the transverse colon in a second patient. The remaining findings in this cohort of patients included diverticular disease and benign polyps.ConclusionDespite the advancement in visualization of anatomy with CT scan and laparoscopic appendicectomy there is still a role for screening colonoscopy in patients greater than 50 years of age with appendicitis particularly if they have associated bowel symptoms or risk factors for CRC.
机译:前言老年人急性阑尾炎相对少见,可能是潜在的大肠癌的首发表现。这些人的结肠镜检查为早期诊断和治疗提供了机会。在1980年代初期,一些小型研究和病例报告支持了老年阑尾炎患者大肠癌(CRC)发病率增加的发现。随着CT扫描和腹腔镜阑尾切除术的出现,增强了盲肠可视化能力目的回顾性分析2017年5月1日至2018年5月31日期间50岁及以上的所有急性阑尾炎患者的12个月回顾性研究,并对术后结肠镜检查结果进行回顾性审查。结果43例患者符合纳入标准。患者的中位年龄为62岁(范围为50-85岁)。 47%的患者是男性。 86%的患者在手术前进行了腹部CT扫描,其中97%的患者可见急性阑尾炎。 100%的病例在手术或病理上均未发现CRC的情况下发现了急性阑尾炎。 46%的患者在结肠镜检查中有相关发现。这包括第二例患者肝弯曲处的恶性阻塞性肿瘤和横结肠的管状腺瘤。该人群的其余发现包括憩室病和良性息肉。结论尽管CT扫描和腹腔镜阑尾切除术在解剖学可视化方面取得了进步,但对于年龄大于50岁的阑尾炎患者进行结肠镜检查仍具有一定的作用,特别是如果他们患有相关的肠症状或CRC的危险因素。

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