Survival Analysis of Type II Diabetes Mellitus Patients: A Case Study at Menellik II Referral Hospital Addis Ababa, Ethiopia

摘要

Diabetes Mellitus is characterized by abnormally high levels of glucose in the blood. It is a chronic disease with a high prevalence and a growing concern worldwide. The main objective of this study was to analyze Survival Analysis of Type II Diabetic patients in Menellik II referral hospital found in Addis Ababa. The study was based on the data which have 151 type II Diabetes Mellitus patients with 10 independent variables. The independent variables that considered in the study were Sex, Age, past medical history, Family History, Complication Status, Regimen type, Specific drug (treatment) type order by Physician, Systolic Blood Pressure of Patients, Diastolic Blood Pressure of Patients and Weight of Patients. The study more explored using survival models such as semi-parametric (Cox PH model) and parametric models (Accelerated Failure Time). The number of patients that recovers from type II Diabetes Mellitus were 116 (76.82%) while the remaining 36 (23.18%) did not recovered from type II Diabetes Mellitus. Finally, the result of this study showed that in Cox PH model past medical history and weight of type II Diabetes Mellitus patients were statistically significant with time to recover from type II Diabetes Mellitus. Likewise age, systolic blood pressure and diastolic blood pressure of patients were time dependent covariates and they were satisfies assumption of proportionality. Accordingly, we obtained gamma distribution was the best fit among other distribution in case of AFT model.